Pseudogenes mitocondriales humanos
Recientemente ( Febrero de 2001 ) han sido descritos los pseudogenes mitocondriales humanos. Estos pseudogenes son una copia casi completa del genoma mitocondrial humano en el cromosoma 17. Es decir, que tenemos también el genoma mitocondrial dentro del nucleo.
Sin embargo estos genes no parecen expresarse; de ahí el nombre de pseudogenes. Curiosamente incluyen también el gen invertido MTND6 en su dirección original.
Reproducimos los datos de la página del NIH ( AF227907 ) :
Homo sapiens chromosome 17 sequence containing mitochondrial genome insertion
LOCUS AF227907 14722 bp DNA PRI 02-FEB-2001
DEFINITION Homo sapiens chromosome 17 sequence containing mitochondrial genome
insertion.
ACCESSION AF227907
VERSION AF227907.1 GI:12656011
KEYWORDS .
SOURCE human.
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 14722)
AUTHORS Kindmark,A., Kilger,C., Benes,V., Haaf,T., von Haeseler,A. and
Paabo,S.
TITLE An almost complete mitochondrial genome in the nuclear genome of
humans and the great apes evolves as a nuclear pseudogene
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 14722)
AUTHORS Kindmark,A., Kilger,C., Benes,V., Haaf,T., von Haeseler,A. and
Paabo,S.
TITLE Direct Submission
JOURNAL Submitted (22-JAN-2000) Max Planck Institute for Evolutionary
Anthropology, Inselstrasse 22, Leipzig D-04103, Germany
FEATURES Location/Qualifiers
source 1..14722
/organism="Homo sapiens"
/db_xref="taxon:9606"
/chromosome="17"
/map="17p11.2"
/clone="H0992Q06"
/note="P1 clone from the Resource Center of the German
Human Genome Project, Berlin, Germany"
misc_feature 491..13801
/note="nearly complete mitochondrial genome"
misc_feature 13802..14046
/note="contains inverted mitochondrial ND6 pseudogene"
BASE COUNT 4614 a 3931 c 2080 g 4097 t
ORIGIN
1 aaaattcaga tgaggatatt aatccaatat tgacaatttc ttcaggaata tcaagtgaat
61 aataatgatt tcactttttt gtttcatttt gtttttgaca taagatcttg ttctgctgcc
121 caggctggag tacagcagca ggatcgtgac tcactacagc ctctgccttc tgggctaaag
181 cagtcctcct acttcagcct cctgtgtaac tgggaccaca gatgcacacc accaggccca
241 ggtaattttt tattttttgg tagagacaga gtcttattat gtttcccaag ctagtcttga
301 acttctgggc tcaagcaagc ctctcacttc agccacccaa aatgctggga tgacaggcat
361 gagtcaccat gcccagcata aagattttat tatgtggaaa taaaaggaca ttaaaatata
421 acttgaaata acccatttct cgcaagtatt aatttttcca ccagttaatc aaatagtgcc
481 aacactagac accaacccca cttccattgc taatcccact aatacactca ccaagacttc
541 aattcctgac ccccatgtct caggatactc ctcaatagcc attgccatag tatatccaaa
601 aacaaccatc gtacccccta gataaattaa aaaaaccatt aaacccatat aacctccccc
661 ataattcaga ataataacac acccaactac accactaata atcaatacta tacccccata
721 aataggagaa ggtttagaag aaaaccctac aaaccctatt actaaagcca cacttaatga
781 taataaagca tatgtgatta atcccacatg gattacaacc acgaccaatg atatgagaaa
841 ccatcatttt atttcgacta taagaacacc aatgacccca acacgtaaaa ctaatccact
901 agtaaaaata atcaaccact cacttatcga tctccccgcc ccatccaaca tctccatatg
961 atggaacttc agcttgcttc ttggtgcctg cttaaccctt caaattatta caggactatt
1021 cctagctata cgctactcac cagacgcctc aaccgccttc tcctcagtcg tccacatcac
1081 tcgagatgta aactatggct gaatcatccg ctacctccat gccaatggcg cctcaatatt
1141 tttcatctgc ctcttcctac atattggccg aggcctgtac tatggcttat ttctctacct
1201 agaaacctga aacattggca tcattctcct actcacaccc atagcaacag ccttcatagg
1261 ctaggtactc ccatgaggcc agatatcctt gaggggccac ggtaatcaca aatctactgt
1321 ccgccattcc ttatgtcgga acagacctgg tgcagtgggt ttgaggtggt tattcagtag
1381 acacacccac tctcacacga ttcttcacct tccactttat cctacctttc attattacag
1441 ccctagtagt cttacaccta ctatttctcc atgagacagc atcaaataac ccctcaggaa
1501 tctcctccca ctccaacaaa attaccttcc acccctacta catgaccaaa gatatcctag
1561 cctattctcc tcctctcacc ctaataacac tagtactgtt ttcacccgac ctcctaactg
1621 atccagataa ctacacccta gccaaccgcc tgaatactcc accccatatt aaacccgaat
1681 ggtattttct atctgcctac gcaatcttat gatccatccc caacaaacta ggaggcgtac
1741 tggccctcct actatcaatc ctcatcctag cagcaattcc cacacttcac atgtccaaac
1801 aacaaagcat aatattctgt ccactaaacc aattcctata ttgactccta attacagatc
1861 tccttatcct cacatgggtt ggaggacaac cagcaagcta ccccttcatc accttcggac
1921 aaacagcatt cgtagtttac tttgctacaa ttctagccct gataccgctt gcctccctac
1981 tcgaaaacaa aatactcaaa tggacctgcc cttgtagtat aaaccaatat attggtcttg
2041 taaaccagaa atggagactc tctcccaagg acaactcaga gaaaaagtac ttgacttcac
2101 catcagcacc caaagctaag attctaattt aaactactct ctgtattctc atgagggagc
2161 cattttgggt acaacccaag tatcgaccca ccccaccata attttatata tatcgtgaat
2221 ttctgctagc caccatgaat attatatagt actataattg cttaactgta catagtacat
2281 atcaaacgaa actcaacaac aactcctccc cacgacgctt acaagcaagg actagaatac
2341 cttaactaac ggtaacacat taaacccacc ctccaaaaga aacttctcaa ccacaagcgt
2401 accaaaaaac actatatatc cttgagtaca tagtacatct aatcgctcat ggtagatagc
2461 acattccagt taaacaagtc ctcgtcaata cggatatccc cctcagatag tggtccgttg
2521 ttcaccatcc tctgtgaaat caatatcctg cagaagagtg ctactcttct tgatccaggt
2581 ccataatact tgggggtagc tataatgaac tgtatccggc atcttgttct tacctcacag
2641 ccataaagtc aagaccaacc acacgttccc cttaaataag acatcacgat ggatcacggg
2701 tctattaccc tattaatcag tcacgggagc tctccatgca tttggtattt taatctgggg
2761 ggtgtgcacg cgatagcatt gtgaaacgct ggccccagag caccctatgt cgcagtgtct
2821 gtctttgatt cctgccccat cccattattg atcacaccta cattcaatat cccaggcgag
2881 catacctatc acaaggtgtt aattaattaa tgcttgtagg acataacaat cagtaaacac
2941 acccacggcc gcttttcaca tcaactctac aataaaattc tgcaaatccc cttcccccat
3001 ctttggcctc accaacccag gaaaagacat ctttgccaaa ccccaaaaac aaaaagcctt
3061 aatccaactc aaccagagcc caaattttta tctttaggct gtacgcattt ttaacagtca
3121 cccctcaact aacacgtctt tttccctctt agcctcactt cacagactct acaaatttag
3181 ttatcccttt ttcagccatc ccattcaacg catgcccgac cactactaaa ccaacaccct
3241 aaactaaccc aaccccaaag gcaaggcttt cccccctacc cattgcttgt atgcccatcc
3301 cctagccttg cttacactgt gcaatcacag tctatgtagc ttaatgaccc aaagcaagac
3361 actgaaaata tctagatggg cctacactgc cccatagaca aataggtttg gtcctagcct
3421 ttctattaac tcttagtaag attacacaag caagcatcgc caccctggtg aaataaccct
3481 ctaaatcact acaatcaaaa ggagtaagta tcaagcacgc attagtgcag ctcaaaacac
3541 tttgcctagc cacaccccca cgggagacag cagtgataaa cctttagcaa taaacgaaag
3601 tttaactgag ctatactaac tttagggttg gttaatttca tgccagccac cacggtcata
3661 cgatgaaccc aagctaatag agactggcgt aaagaatgtt ttacattatc cctcaataaa
3721 gctaaatttc acctaagttg tagaaaaccc tagttgatat aaaacaaact acgaaagtgg
3781 ctttaatatt tctgaataca caatagcgaa gattcaaact gggattagat accccactat
3841 gctcagccct aaacttcaac agttaaatca acaaaactgc tcgccagaac actaggagca
3901 acagcttaaa actcaaagga cctggcggtg cttcacatcc ctctagagga gcctgttcta
3961 taatcgataa accccaattc acctcaccac ctcttgctca acccatatac cgccatcttc
4021 agcaaaccct gacaaaggcc acaaagtaag cacaagtatc tacataaaaa tgttaggtca
4081 aggtgtagcc tatgaggtgg caagaaatgg gctacatttt ctaccccaga aaattctaca
4141 ataaccctta tgaaacctga gggtccaagg aggatttagt agtaaattaa gaacagagtg
4201 cttaattgaa tagggccata aagcacgcac acaccaccca tcaccctcct caagtatatt
4261 tcaaggacta tctaactaaa acccctatgc atttatatag aggagataag ttggataaac
4321 caaggtgtag cttaacataa agcaccctgc ttacacctgg gagatttcaa tttaatttga
4381 ccaccctgag ctaattctag ccccaaaccc aactaattct actaccaaat aacctcaact
4441 aaaacattta cccaaataaa gtataggcga tagaaatgat atctcggcac aatagacata
4501 ataccgcgat ggaaagatga aaaaacataa ccaagcataa agtagcaagg acaaacccct
4561 ataccttctg cataatgaat taactagaaa taactttaca aagagaacca aagccaagac
4621 ccccgaaacc agacgagcta cctaagaaca gctgaaagag cacacccatc tatgtagcaa
4681 aatagtggga agattcatag gtagaggtga caagcctacc gagcctggtg atagctggtt
4741 gtccaagata gaatcttagt tcaactttaa atttatctac agaaccagct aatgcctttg
4801 taaatttaac tgttagtcta aagagggaca gctctttaga cactaggaaa aaaccttgta
4861 gagagagtaa aaaatataac ttccaaagtt ggcctagaag aagcgatcaa ttaagaaggc
4921 gttcaagctc aacacccaac cacccaaaaa attccaaaca cataactgaa ctcctcacat
4981 cacattggac caatctatca tttcatagaa gaaataatgt tagtataagt gacatgcaaa
5041 cattctcctc cgcataagcc tacatcagac caaaatactt cactgacaat taacagccca
5101 atatctataa ataatcaatg aaaccattat tacccacact gttaacccaa cacaggcatg
5161 cttacaagga aaggttaaaa aaagtaaaag gaactcagcg aatcttaccc ctcctgttta
5221 tcaaaaacat cacctctagc attaccagta ctagaggcac cacctgccca gtgacatatg
5281 tttaatggct gcggtaccct aaccgtgtaa aggtagcata atcacttgtt ccttaaatag
5341 ggacttgtct gaatggctcc acgagggttc agctgtctct tactttcaac cagtgaaatt
5401 gacctgcccg tgaagaggcg gacataatac aacaagacga gaagacccta aggagcttta
5461 atttatgaat gcaaacaaga ccaaataggc ccgcaggccc taaactacca gacctgcgtt
5521 aaacatttcg gttggggcga cctcggagta taacctaacc tccgagcaac atatgctgag
5581 actataccag tcaaggcgaa tatccacata caattgaccc aataatttga ccaacggaac
5641 aagttaccct agtgataaca gtacaatcct attctagggt ccacatcgac agtagcatta
5701 acgacctcga tgttggatca ggacatccca atggtgcagc cgctattaaa ggttcgtttg
5761 ttcaacgatt agagtcctat gtgatctgag ttcagaccgg agtaatccag gttggtttct
5821 atctattcta catttcttcc agtacgaaag gataagagaa atggggccca cttcataaag
5881 tgcccctgcc ccatagatga tattatctca gcattttact gtacccacac ccacccaaga
5941 acagggtttg ttaagatggc agaccccagc aattgcataa aatttaaaac tttacaacca
6001 gaggttcaac ccctcttctt aacaacatgt ccataactaa ccttctactt cttattgtac
6061 ctatcctaat cgccatggca ttcttcatgc taactgaatg aaaaatccta ggctacatgc
6121 aactacgcaa agggcccaat attgtaggcc cctatggact attacaacct tttgccgatg
6181 ccataaaact ctttaccaaa gaatccttaa aaccctcaac gtcaactgtt accctctaca
6241 tcactgcccc aaccttagcc ctctctattg cccttctact atgaactccc ctccctatac
6301 ctaaccccct agttaatctt aacttaggcc ttctattcat tctggctaca tccagcctag
6361 ctgtctactc tatcctatga tcaggatgag catcaaactc aaactatgcc ctgatcggcg
6421 cattatgagc agttgcccaa acaatttcat acgaagttac cctagctatc atcctattat
6481 cgatcctact aataagtggc caattcaatc tctgcaccct cattagaaca caagaacacc
6541 tctgactact cctaacatca tgacccctag ctataatatg atttatttcc acactagcag
6601 aaaccaatcg agctgctttt gaccttactg aaggagaatc agaactagtc tcaggcttca
6661 acattgaata tgctgcaggc ccattcgccc tattctttat agccgaatac ataaatatca
6721 ttaaaataaa tgccctaact gccataatct tcctaggtac aatatataat attcacctac
6781 cagaactcta cacaatatgc ttcaccatta aaaccctatt cctaacctct ctatttttat
6841 gaatccgaac agcatacccc cgattccact acgatcaact catgtatctc ttatgaaaaa
6901 atttcttacc atttacacta gcactactta tatgatacat ctcaatatcc gctacaattt
6961 ccaacattcc cccctaaact taagaaatat gtctgacaaa agagtgactt tgatagagta
7021 aataatagag gtttgaatcc tcttatttct aggaccatag gaattgaacc tatccctgag
7081 aatccaaaat tctccgtgcc acgtgtcaca ccctatcctg gagtaaggtc agctaaataa
7141 gctatcaggc ccatacccag aaaatgttgg ttatatcctt cccgtactaa tcaatccact
7201 ggcccaacct gtcatctact ccaccgtttt cacaggtaca ctcattgcaa cattaagctt
7261 gcactgattt tttacctgga caggattgaa aataaacata ctagctttta tcccaatttt
7321 aattaaaaaa ataaaccccc gctctacaga aactgctatc aaatactttc tcacataagc
7381 aaccacatct ataatcctca taatagctat cctctccaac aatgtactct ccggacaatg
7441 aaccacaacc aacaccacca acaaatactc atcattaata atcacaacag ccctagtaat
7501 aaaactagga atagcccctt tccgtttctg agtcccagaa gtcactcaag gaacccctct
7561 aatatccagc ctacttcccc tcacatgaca aaaattagcc cctatttcaa ttatatatca
7621 aatctcccca ttaataaaca ttctccttac cctttcaatc ttatccatta tagtgggtag
7681 ctggggtgga ctgaaccaaa cccaactatg taaaatccta gcatactcct caatcaccca
7741 tataggctga ataatagcag tactagcata caacccaagt atcaccattt tcaacctaat
7801 catctatatc attctaacaa ccaccacatt cctggtactc aacttgaact ctagcactac
7861 aaccctacta ctgtgccgca cttgaaataa actaacctga ctaatacccc taatcccatc
7921 taccctacta tcactaggag gccttccccc actaactggc tttctaccca aatgatttat
7981 cattgaagaa ttcacaaaaa ataacaacct cattatcccc actaccatag ccattattac
8041 tctctttaac ctatatttta acatacgctt aatctactct gcttcaatta cactattccc
8101 catatccaac aacgtaaaaa taaaatgaca tttgaaatac aaaatccaca ccactcttcc
8161 ccacactcac tgtccttacc accctcctcc taccaatctc tccacttaca ctacccacct
8221 catataaatt tatgttaaac gcagactaag agccttcaaa gcccttagta agttaataat
8281 acttaatttc tgcagcaccc aaggactgca aaaccctact ttgcatctac tgaacgcaaa
8341 tcagccactt taattaagct aagcccttgc tagatcaatg ggacttaaac ccacaaaaat
8401 ttggttaaca gctaaatacc ttaatcaact ggcttcaatc tacttctccc gccgcaaggg
8461 aaaaaaggcg ggagaagccc aggcaggatt gaagctgctt ctttgaattt gcaattcaac
8521 atgaaaggca cctcagggct ggtaaaaaga gagtttttag atttacagtc taatgctttg
8581 ctcagccatc ttacccacta atgttcgcca accgctgact attctcaaca aatcataaag
8641 atatcggaac actatattta ttgtttggtg catgagctgg agtcttgggc acagccttaa
8701 gcctccttat tcagactgaa ctaggtcaac ctggcaacct tctaggtaac gaccacatct
8761 acaacgtcat cgtcacagcc cacacattct tcataatctt tttcatagta atgtctatca
8821 taattggagg ttttggcaat tgactggtcc ccctgataat tggcgcccct gacatggcat
8881 ttccctgcgt aaataacata agcttctggc tccttcccca cccctttcta ctactgctgg
8941 catctgctat gatagaagct ggtgccggaa caggttgaac ggtttaccct cctttggcag
9001 gaaactattc ccatccagag gcctctgtag acctaaccat tttctccctt catctagcag
9061 gtgtctcctc tattctagga gctattaatt tcatcaccac aattattaac ataaaacccc
9121 ctgccatata tcaataccaa acgcccctct ttgtctgatc tgtcctaatc acggcagtcc
9181 tactcctcct ctccttccag tcttggccgc tggcattact atactgctaa cagaccgtaa
9241 ccttaatatt acctttttga cctggccgga gaaggggacc ctatcctata acaacaccta
9301 ttttgattct ttggtcaccc tgaagtctat attctcatcc taccaggctt tggaataatt
9361 tctcacatcg taccatatta ttccggaaag aaagaaccat tcgggtacat aggtatggtc
9421 tgggctataa tatcaattgg cttcctaggg tttattgtat gagcccatca tatattcaca
9481 gtagggatag atgtagacac acgagtttac tttacctctg tcactataat tattgccatc
9541 cccactggcg tcaaagtatt tagctgactt gctacgctcc atgggggtaa caccaaatgg
9601 tccaccgcag tactctgagc cctaggattc atcttccttt ttacagtggg tggcctaacg
9661 gacattgtac tagcaaactc atcattagac atcgtactac atgatacata ttatgttgtg
9721 gcccactttc actacgttct atcaatagga gctgtgttca ccatcatggg gggcttcatc
9781 cactgatttc ccttattctc aggctacaca ctcggccaag cttatgccaa aattcacttt
9841 gccatcatat ttgtaggcgt aaatctaacc ttcttcccgc agcactttct cggcctatct
9901 gagatgtccc gatgttattc cgactacccc gatgcatata ccacaggaaa tattttatca
9961 tctgtaggct cattcatctc cctaaaagca gtagtgctaa taattttcat aacctgagag
10021 accttcgctt caaagcgaaa agtcctaata aatgagcaac cttccactaa cctagagtgg
10081 ctgtagggat gccctccacc ctaccataca tttaaagaac cagtctacat aaaacctaga
10141 caaaaaagga aggaattgaa cctcctaagg ctggtttcaa gccagcctca taacccctat
10201 gactttttca acaagatatt aggaaaacta tttcataact tcgtcaaagt taagttacag
10261 gttaaacccc gtatatctta atggcacacg cagcccagct aggtcttcaa gacgccacat
10321 cccctatcat agaagagcta atcgccttcc atgatcacgc cctcataatc atctttctta
10381 tcagctttct agttttatac gccctcttcc taacaattac aacaaaacta acactaacat
10441 cacagacgcc caagaaatag aaactgtttg aatgattcta cctgccatta tcctagtcct
10501 aattgccctt ccatccctac gtatcctgta cgtaacagat gaaatcaatg acccttcttt
10561 taccattaaa tcaatcggac accaatgata ctgaacctat gaatacacca attatggagg
10621 attaattttc aactcttata tacttccacc actattctta gacccaagtg accttcgact
10681 tcttaaagtt gataatcgag tagtccttcc aattgaagcc cctgttcata taataattac
10741 atcacaagac gtcctacact catgaactgt ccccacatta ggcttaaaaa cagatgtaat
10801 ccccggacgc ctaaaccaaa ccacattcac cgccatacga ccaggagtat actacggtca
10861 atgctcagaa atctgcggag ctgaccatag cttcataacc atcattctag aactaatccc
10921 gctaaaaatc tttgcaatag gacctgtatc cactttatag gctaccgccc actctcttaa
10981 taaggttcac tgtagagctg acccagcatt aaccttttaa gttaaagact aagagaatcg
11041 ctatctcttt acagtgacat gcctcaacta gacaccacca tatgacccac tatcgtcgca
11101 tcaatactcc tcacattatt actcatcatt caactaaaag tactaaacac aaactaccat
11161 ctgcctacct cactaaaaat tattaacatg caaaaccaca ataatccttt agagtcaaaa
11221 tgaacgaaaa tctgtttact tcattcattg cccccacaat tctaggcctt ccagctgcag
11281 tgccaatcgt tctatttctc cccatgctga ttccagcttc caaacacctt atcaacaacc
11341 gattaattac cactcaacag tgactaattc aactcaccct aaaacaaata ataacaataa
11401 ataacattaa aggacgaacc tgatccctca tgctaatatc cctaattatc ttcattgcta
11461 caaccaatct cctcgggctc ttgcccactc attcacacca actacccaac tgtcataaac
11521 ctggccatgg caatccccct atgagcaggt gcagtaatta caggcttccg ctttaaaacc
11581 aaaaatacct tagcccatct cttgccacaa ggcacaccct cacccctcat tcccatacta
11641 attattatcc aaaccatcag cctatttatc caaccaatag ccctagccat gcccctaact
11701 gctaatatta tggcaggcca tctgctcata cacttaatca gaagtgccac actagcgcta
11761 tcaactatca acctccccac aacctcaatc atcttcacaa ttttgatttt actgacgatt
11821 ctcgaaatcg ctgtcgccct gattctagcc tatgttttca cactcctagt gagcctctac
11881 ctacatgaca atacataatg gctcaccaat cacatgccta tcacatagta aaacccagcc
11941 catgacctct aacaggggcc ctttcagccc tcctaatgac atccggccta gctatatgat
12001 tccactttta ctctaccacc ctactaacac taggcctact gaccaatgca ctaaccatat
12061 accagtgatg atgtgatgtt gtacgagaag gtacatacca agaccaccac acagtacccg
12121 tccaaaaagt ccttcggtat ggaataattt tattcatcat ctcagaagtc tttttcttcg
12181 ctggattctt ctgagcattc taccactcca gcctagcccc cacccctcaa ctaggaggac
12241 actgaccccc aacaggcatc actccactca accccctaga agtcccactc ctaaacacat
12301 ctgtactact cgcatcggga gtttcaatta cttgagctca ccatagccta atagagaaca
12361 attgtaatca agcaattcaa gcactactta tcacaatctt actaggcatc tacttcaccc
12421 tcctacaagt ttcagaatac tttgaagccc cctttactat cgccgatggt atgtatggtt
12481 caacatgttt tgtagctacg ggcttccacg ggctccccgt catcattggt tcaacattcc
12541 ttactgtttg ccttatccgc caactattat atcattttac atccaagtac cacttcggct
12601 tcgaagccgc tgcttgatac tgacactttg tagatgtagt ttgactattc ctatatgtct
12661 ctatctactg gtgaggatct tactctttta gtatagacag taccactgac ttccaattaa
12721 ctagtttcga taacactcga aaaagagtaa taaacctggc actagcccta acagtcaaca
12781 ccctcctggc cccattacta ataaccatca cattttgatt accacaactt aatatctaca
12841 taggaaagtc taacccttat gaatggggtt tgacccacta tcctctgctc gcattccctt
12901 ctccataaaa ttcttcttga ttgctatcac ctttttatta tctgacctag aaattgccct
12961 attactaccc ctaccgtgag ccctccaaac aaccaatcta ccactaacag ttgtatcatc
13021 actcacatta gttactatct taatcctaag tttgacttat gaactatccc agaaaaggtt
13081 agactgagtc aaattggtaa gtagtttaac agacaaaaac aatgattttg acttgttaga
13141 ttatgatagt catacttaca aaatgcccct catctacata aacattacat tagcatttac
13201 tacctcactg ttaggaatac taatctatcg ctcacaccta acgtcctccc tactatgcct
13261 agaggggata atattatctc tattcatcgt aaacaccctc ataaccctaa acacacactc
13321 tcccttaatt aacatcatac ctatcaccat attagtcttt gctgcctgtg aagcagcagt
13381 gggcctcacc ctactagtct caatttctaa cagatacggt ctagatatgt acataactta
13441 aacttactcc aatgttaaaa ttaattatcc ctacaatcat actacttcca acaacatgac
13501 tctctaaaaa ccatataatt tgaattaaca taaccactca cagcctaatt aacagctcta
13561 tcccactgtt atttttcaac caagccaacg acaatctatt tagctactct ctttctcctc
13621 tgaccccctg atgacacccc ttctaatact aacagcctga cttctacctc ttatgatcat
13681 agcgagtcaa tgccacttat ctaacaagtg ccccttacgg aaaaaaactt tacctgtctg
13741 tactaatcac ccttcaaatc tccctgatca taacattcat ggccacagaa ctaatcatat
13801 tgattattag tggtgtagtt gggtgtgtta ttattctgaa ttatggggga ggttatatgg
13861 gtttaatagt tttttaaatt tatctaggag tatgatggtt gtttttggat atactacagc
13921 aatggctatt gaggagtatc ctgagacacg ggggtcagga attgaagtct tggtgagtgt
13981 attagcggga ttatcaatgg aagtggggtt ggtcttatga gtgaaggagt atgatggggt
14041 ggtggtagtg gtcacattct ttgctgaaca aacggtacct caaataactt catacaaata
14101 ctactgggaa acttagcatt ttattaaaat gtttaaattt cctattttat caaatctaac
14161 atattagtaa taatatattc cttttattca actttaaagt tctattcaac aatagcaatt
14221 tataatttta tattattaaa tgttattcat acagtttaat aattttataa tttagcatta
14281 atgaaaccag cacagacaat ataatgttca tgatatttta tgtatatgtt taacatacac
14341 atacataatt caacattaat ggcttcctta attaccatta atattataat tttatattat
14401 catttaagtt tgcccttcta ttttaatatt agatgtctta gcatccatca gttctatcaa
14461 gctcttctca ctggttcttc tttgaattcc agacatggcc acaatcttct cttctaaaat
14521 tctaaaatct gagggctctc gctggctggg tgctgctgga agaactgtaa cttggttgtt
14581 atctcaacgg tattttattt taaatgtttc aattaaaaga agtttttaaa aatgtggaat
14641 cctgagaata ttcacttttt aaatacaatg ggaatgtatt taatgtatcg ctgaagtctg
14701 ttctcctcgt ttgatccagg gt
//